Lessons for Responsible Geroscience from the History of Longevity

Wohns N, Promislow D. Lessons for Responsibile Geroscience from the History of Longevity. AMA J Ethics. 2025;27(12):E866-872. doi: 10.1001/amajethics.2025.866.

Advances in public health, medicine, and technology since the mid-19th century have redefined what is considered “natural” for human beings. This article situates contemporary geroscience in that historical context. The development of gerotherapies must be guided by historical insight, ethical foresight, and a commitment to justice. Since extending lifespans has important societal consequences, how aging research will affect future generations should be prioritized. Equitable access to gerotherapies, as well as an emphasis on social responsibility and the influence of community on health and longevity, must remain central to any vision of the future of aging.

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